Fatal Liver Failure Secondary to Chemotherapy Induced Hepatitis-B Virus Reactivation in a Patient with Acute Myeloid Leukemia*
نویسندگان
چکیده
virus surface antigen (HBsAg) is known to promote viral replication, and when immunosuppressive treatment is stopped the return of immunocompetence can be followed by liver damage of varying degrees of severity, including fulminant hepatitis. Hepatitis B virus (HBV) reactivation of various degrees may develop in 20-50% of HBsAg positive patients undergoing immunosuppressive or cytostatic treatment (1). We report a patient with acute myeloid leukemia (M1) who developed fatal liver failure from reactivation of HBV after chemotherapy.
منابع مشابه
Reactivation of hepatitis B.
Reactivation of hepatitis B refers to the abrupt increase in hepatitis B virus (HBV) replication in a patient with inactive or resolved hepatitis B. Reactivation can occur spontaneously, but more typically is triggered by immunosuppressive therapy of cancer, autoimmune disease, or organ transplantation. Reactivation can be transient and clinically silent, but often causes a flare of disease tha...
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